The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms. Marine Beck, Mathilde Baranger, Ahlam Moufok-Sadoun, Emilie Bersuder, Isabelle Hinkel, Georg Mellitzer, Elisabeth Martin, Laetitia Marisa, Isabelle Duluc, Aurelien de Reynies, Christian Gaiddon, Jean-Noel Freund, Isabelle Gross. Oncogene. 2021 Jan;40(3):522-535.

A Core Response to the CDX2 Homeoprotein During Development and in Pathologies. Victor Gourain, Isabelle Duluc, Claire Domon-Dell, Jean-Noël Freund. Front Genet. 2021 Oct 25;12:744165

CDX2 controls genes involved in the metabolism of 5-fluorouracil and is associated with reduced efficacy of chemotherapy in colorectal cancer. Jean-Baptiste Delhorme, Emilie Bersuder, Chloé Terciolo, Ourania Vlami, Marie-Pierrette Chenard, Elisabeth Martin, Serge Rohr, Cécile Brigand, Isabelle Duluc, Jean-Noël Freund, Isabelle Gross.Biomed Pharmacother. 2022 Mar;147:112630.

General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions. Susanna Säisä-Borreill, Guillaume Davidson, Thomas Kleiber, Andréa Thevenot, Elisabeth Martin, Stanislas Mondot, Hervé Blottière, Alexandra Helleux, Gabrielle Mengus, Michelina Plateroti, Isabelle Duluc, Irwin Davidson, Jean-Noel Freund. 
Cell Death Differ. 2023 Mar;30(3):839-853.

Circulating Tumor Cell Lines: an Innovative Tool for Fundamental and Translational Research. Guillaume Belthier, Zeinab Homayed, Céline Bouclier, Muriel Asari, Julie Pannequin. 
J Vis Exp. 2021 Dec 25;(178).

CD44v6 Defines a New Population of Circulating Tumor Cells Not Expressing EpCAM. Guillaume Belthier, Zeinab Homayed, Fanny Grillet, Christophe Duperray, Julie Vendrell, Ilona Krol, Sophie Bravo, Jean-Christophe Boyer, Olivia Villeronce, Jihane Vitre-Boubaker, Diana Heaug-Wane, Françoise Macari-Fine, Jai Smith, Matthieu Merlot, Gérald Lossaint, Thibault Mazard, Fabienne Portales, Jérôme Solassol, Marc Ychou, Nicola Aceto, Emilie Mamessier, François Bertucci, Jean Marc Pascussi, Emmanuelle Samalin, Frédéric Hollande, Julie Pannequin. Cancers (Basel) 2021 Oct 2;13(19):4966. 

Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme. Guillaume Jacquemin, Annabelle Wurmser, Mathilde Huyghe, Wenjie Sun, Zeinab Homayed, Candice Merle, Meghan Perkins, Fairouz Qasrawi, Sophie Richon, Florent Dingli, Guillaume Arras, Damarys Loew, Danijela Vignjevic, Julie Pannequin, Silvia Fre. Elife. 2022 May 11;11:e76541.

Regulation of Src tumor activity by its N-terminal intrinsically disordered region. Emilie Aponte, Marie Lafitte, Audrey Sirvent, Valérie Simon, Maud Barbery, Elise Fourgous, Yvan Boublik, Mariano Maffei, Florence Arman, Romain Hamelin, Julie Pannequin, Philippe Fort, Miquel Pons, Serge Roche. Oncogene. 2022 Feb;41(7):960-970.

Fecal microbiota transplantation in a rodent model of short bowel syndrome: A therapeutic approach? Fourati S, Dumay A, Roy M, Willemetz A, Ribeiro-Parenti L, Mauras A, Mayeur C, Thomas M, Kapel N, Joly F, Le Gall M, Bado A and Le Beyec J (2023).Front. Cell. Infect. Microbiol.  3:1023441.

Metabolism of Alimentary Compounds by the Intestinal Microbiota and Health. François Blachier. Editeur Springer. Le livre est disponible en version électronique sur Springer Link, Amazon, Google books, FNAC etc. La version papier sera disponible début juin 2023 sur ces mêmes sites.

Assessment of Dendrigrafts of Poly-l-lysine Cytotoxicity and Cell Penetration in Cancer Cells. Fabien Granier, Sébastien Marie, Zahra Al Amir Dache, Julien Aityaya, Thibault Mazard, Laurent Garrelly, and Corinne Prévostel. ACS Appl. Polym. Mater. 2022, 4, 2, 908–919. https://pubs.acs.org/doi/10.1021/acsapm.1c01354.

A straightforward method to quantify circulating mRNAs as biomarkers of colorectal cancer. Grosgeorges M, Picque Lasorsa L, Pastor B, Prévostel C, Crapez E, Sanchez C, Frayssinoux F, Jarlier M, Pezzella V, Monard L, Ychou M, Thierry AR, Mazard T, Blache P. Sci Rep. 2023 Feb 15;13(1):2739.doi:10.1038/s41598-023-29948-4.

RIP140 Represses Intestinal Paneth Cell Differentiation and Interplays with SOX9 Signaling in Colorectal Cancer. Gleizes A, Triki M, Bonnet S, Baccari N, Jimenez-Dominguez G, Covinhes A, Pirot N, Blache P, Yuan R, Győrffy B, Cavaillès V, Lapierre M. Cancers (Basel). 2021 Jun 26;13(13):3192. doi: 10.3390/cancers13133192. 

Revisiting definition and assessment of intestinal trans-epithelial passage. Ilchmann-Diounou H, Buleon M, Bacquie V, Theodorou V, Denis C, Menard S. Cell Mol Life Sci. 2021 Nov 3. doi: 10.1007/s00018-021-04000-8. Online ahead of print. 

SCFA: mechanisms and functional importance in the gut. Martin-Gallausiaux C, Marinelli L, Blottière HM, Larraufie P, Lapaque N.Proc Nutr Soc. 2021 Feb;80(1):37-49. doi: 10.1017/S0029665120006916. Epub 2020 Apr 2.PMID: 32238208 Free article. Review.

Fecal Microbiota Transplant from Human to Mice Gives Insights into the Role of the Gut Microbiota in Non-Alcoholic Fatty Liver Disease (NAFLD). Burz SD, Monnoye M, Philippe C, Farin W, Ratziu V, Strozzi F, Paillarse JM, Chêne L, Blottière HM, Gérard P.Microorganisms. 2021 Jan 19;9(1):199. 

Prenatal exposure to low doses of fungicides corrupts neurogenesis in neonates. Wang Y, Lafon PA, Salvador-Prince L, Gines AR, Trousse F, Torrent J, Prevostel C, Crozet C, Liu J, Perrier V. Environ Res. 2021 Apr;195:110829. doi: 10.1016/j.envres.2021.110829. Epub 2021 Feb 4. 

Circulating nuclear DNA structural features, origins, and complete size profile revealed by fragmentomics. Sanchez C, Roch B, Mazard T, Blache P, Dache ZAA, Pastor B, Pisareva E, Tanos R, Thierry AR. JCI Insight. 2021 Apr 8;6(7):e144561. doi: 10.1172/jci.insight.144561. 

Blood contains circulating cell-free respiratory competent mitochondria. Al Amir Dache Z, Otandault A, Tanos R, Pastor B, Meddeb R, Sanchez C, Arena G, Lasorsa L, Bennett A, Grange T, El Messaoudi S, Mazard T, Prevostel C, Thierry AR. FASEB J. 2020 Mar;34(3):3616-3630. doi: 10.1096/fj.201901917RR. 

Alternative stable states in the intestinal ecosystem: proof of concept in a rat model and a perspective of therapeutic implications.Van de Guchte M, Burz SD, Cadiou J, Wu J, Mondot S, Blottière HM, Doré J.Microbiome. 2020 Nov 6;8(1):153. doi: 10.1186/s40168-020-00933-7.PMID: 33158453 Free PMC article. 

Hypoxia differently modulates the release of mitochondrial and nuclear DNA. Otandault A, Abraham JD, Al Amir Dache Z, Khalyfa A, Jariel-Encontre I, Forné T, Prévostel C, Chouaib S, Gozal D, Thierry AR. Br J Cancer. 2020 Mar;122(5):715-725. doi: 10.1038/s41416-019-0716-y. Epub 2020 Jan 13. 

Modulating PKCα Activity to Target Wnt/β-Catenin Signaling in Colon Cancer. Dupasquier S, Blache P, Picque Lasorsa L, Zhao H, Abraham JD, Haigh JJ, Ychou M, Prévostel C. Cancers (Basel). 2019 May 18;11(5):693. doi: 10.3390/cancers11050693. 

A Short SOX9 Peptide Mimics SOX9 Tumor Suppressor Activity and Is Sufficient to Inhibit Colon Cancer Cell Growth. Blache P, Canterel-Thouennon L, Busson M, Verdié P, Subra G, Ychou M, Prévostel C. Mol Cancer Ther. 2019 Aug;18(8):1386-1395. doi: 10.1158/1535-7163.MCT-18-1149. Epub 2019 May 15.

Beneficial effects of Saccharomyces boulardii CNCM I-745 on clinical disorders associated with intestinal barrier disruption. Terciolo C, Dapoigny M, Andre F. Clin Exp Gastroenterol. 2019 Feb 11;12:67-82. doi: 10.2147/CEG.S181590. eCollection 2019. Review.

Quantifying circulating cell-free DNA in humans. Meddeb R, Dache ZAA, Thezenas S, Otandault A, Tanos R, Pastor B, Sanchez C, Azzi J, Tousch G, Azan S, Mollevi C, Adenis A, El Messaoudi S, Blache P, Thierry AR.Sci Rep. 2019 Mar 26;9(1):5220. doi: 10.1038/s41598-019-41593-4.

Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells. Marinelli L, Martin-Gallausiaux C, Bourhis JM, Béguet-Crespel F, Blottière HM, Lapaque N. Sci Rep. 2019 Jan 24;9(1):643. doi: 10.1038/s41598-018-37019-2.